Institue of Green Science Research
TAML Overview
TAML, tetra-amido macrocyclic ligand, catalysts, are mimic enzymes developed by Professor Terrence Collins and his research group at Carnegie Mellon University that can decompose micropollutants in water solutions into their basic harmless compounds. Micropollutants are particles, often found in pharmaceuticals, fertilizers, pesticides, and more, that are toxic at extremely small concentrations. This technology serves as a cost-effective, efficient, and environmentally friendly solution to fighting against the increasing water pollution across the globe.
A variety of TAML variations have been developed over the course of the years to present effectiveness against different types of compounds in various conditions. The first variation, B* is shown in the figure on the right.
Molecular structure of the basic TAML B*
My Research - Indirect kII
My research focused on analyzing the kinetics of the three-way inhibition reaction between B* TAML, a colored dye, and a colorless substrate via UV-Visible (UV-Vis) spectroscopy. Examining this interaction allows for more accurate understanding of the B* TAML kinetics, as well as provides a new method of analysis with UV-Vis spectroscopy.
Through my research, I developed a new understanding of the kinetics and interactions of aqueous systems, as well as a trained grasp of handling UV-Vis spectroscopy with care and precision. I gained experience in writing papers, delivering presentations, and discussing scientific research with other academics, which helped me become more confident in my own knowledge and research.
I had the opportunity to present the results of my research at the Spring 2019 Meeting of the Minds Undergraduate Research Symposium to a variety of audiences, including other students, professors, and anyone interested! Check out my poster below, or click here: Meeting of the Minds 2019 Poster
A more detailed report of my 5 semesters of research can be found here: Indirect kII: Degradation of Phenol and Propranolol by B* TAML with Safranin-O and Orange II Dyes
My research allowed me to co-author this paper published by my mentor: Oxidative Catalysis by TAMLs: Obtaining Rate Constants for Non-Absorbing Targets by UV-Vis Spectroscopy
